Electrical modeling of a nanopore measurement

Posted on Feb 6, 2014

An illustration of the electronic impedances of a solid-state nanopore chip. (b) Simplified circuit schematic of the voltage-clamp current preamplifier. (c) Circuit design of the low-noise current source that substitutes for a feedback resistance (RF). (d) An example transient current pulse, characteristic of a single-molecule event such as th

Electrical modeling of a nanopore measurement
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e one illustrated. (e) Dominant sources of noise power spectral density, illustrated as a function of frequency. J. K. R. , K. L. S. and M. D. developed the platform concept. J. K. R. designed the amplifier and measurement system. J. K. R. , K. L. S. , M. W. and M. D. planned experiments. M. W. and C. A. M. fabricated nanopores. J. K. R. and M. W. performed nanopore experiments and analyzed data. J. K. R. and K. L. S. wrote the manuscript. All authors edited the manuscript.

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